WEDNESDAY, 2 OCTOBER
13:30 Registration
15:30 Opening Coral Barbas, Vicechancellor of Research, CEU-USP; Beatriz de Pascual-Teresa, Organizing Committee, CEU-USP; Antoni Torrens, President SEQT
Chairperson
Javier Rojo/Antoni Torrens
16:00 Inaugural Lecture: "Antibody-Based Therapeutics for Cancer Therapy"
Peter Senter, Seattle Genetics, EEUU
17:00 IS1: “Synthetic biology and smart therapeutic systems”
Guillermo de la Cueva Méndez (BIONAD- Centro Andaluz de Nanomedicina y Biotecnología, Málaga, Spain)
17:30 IS2: “Glycofullerenes for Biological Applications”
Nazario Martín León (Universidad Complutense de Madrid, Spain)
18:00 SEQT Awards
18:30 OC1: “A new strategy to gain selectivity within the gelatinases subfamily”
Benjamin Fabre. (Universidad CEU San Pablo, Madrid, Spain) Ramón Madroñero SEQT Award
20:00 Welcome Cocktail
THURSDAY, OCTOBER 3RD
MORNING SESSION
Chairperson:
Mª José Camarasa/Mª Luz López
09:00 IS3: “3D Pharmacophore Models: Efficient Tools for Hit Identification,Lead Optimization, and Ligand Profiling”
Thierry Langer (Prestwick Chemical, Illkirch, France)
09:30 IS4: “Integrating Intramolecular Hydrogen Bonding (IMHB) considerations in Drug Discovery using lipophilicity as a Tool”
Giulia Caron (University of Turin, Italy)
10:00 IS5: “Nucleic acids in G-quadruplex conformations as innovative targets against cancer”
Stefano Alcaro (Universitá "Magna Graecia", Catanzaro, Italy)
10:30 Coffee Break
11:00 IS6: “ORL-1 Antagonists: Lead Optimization and PET Tracer Development”
Angeles Martínez Grau (Lilly, S.A., Madrid, Spain)
11:30 IS7: “The asymmetric architecture of G protein-coupled receptor heteromers with G proteins explains signalling cross-talk”
Peter McCormick (Universidad de Barcelona)
12:00 Oral Communications
Communications (OC2-OC5)
OC2: “Synthesis and Pharmacological Evaluation of Acetaminophen Analogues with Antinociceptive Properties”
Pilar Goya (Instituto de Química Médica, CSIC, Madrid, Spain)
OC3: “Synthesis and Pharmacological Evaluation of Acetaminophen Analogues with Antinociceptive Properties”
Pilar Goya (Instituto de Química Médica, CSIC, Madrid, Spain)
OC3: “Applications of click chemistry in sphingolipid research”
Antonio Delgado (IQAC-CSIC, Barcelona, Spain)
OC4: “Computational chemistry for identifying differences among choline kinases active sites”
Lucía Serrán Aguilera (Universidad de Granada, Spain)
OC5: “Impact of fluorination on proteolytic stability of peptides: a case study using α-chymotrypsin and pepsin”
Jeremie Mortier (Free University of Berlin, Germany)
13:00 Lunch
AFTERNOON SESSION
Chairperson:
Pilar Goya/Julio Álvarez Builla
15:00 IS8: “Amino Acid-Derived β–Lactams: Synthesis, Biological Activity and Beyond”
Rosario González Muñiz (Instituto de Química Médica, CSIC, Madrid, Spain)
15:30 OC6: “New non-metathetic processes catalysed by ruthenium complexes for the synthesis of heterocycles”
Javier Pérez-Castells (Universidad CEU San Pablo, Madrid, Spain)
15:45: Poster Session and Coffee
16:45 Oral Communications (OC7-OC8)
OC7: “Merging of pineal neurochemicals. pharmacological profiles and neurogenic potential”
Mario de la Fuente Revenga (Instituto de Química Médica, CSIC, Madrid, Spain)
OC8: “Drugging the von hippel lindau E3 ubiquitin ligase: potential drugs and useful chemical tools”
Carles Galdeano (University of Dundee, Dundee, UK)
19:30 Cultural evening:
"Discover most unknown Madrid`s old town,even for locals; in a 1,30-1,45 hrs aprox walking tour seeing highlights bringing back its ancient past,legends,alleyways,monuments and curiosities with a fully licensed guides that will make you travel through the time" Underground: Puerta del Sol metro station.
FRIDAY, OCTOBER 4TH
MORNING SESSION
Chairperson
Jordi Gracia/Javier Fernández Gadea
09:00 IS9: “Next-Generation Inhibitors for Kinases, Histone-Deacetylases, and Histone Methyltransferases: The discovery of Slowness”
Gerhard Müller (Mercachem, The Netherlands)
09:30 IS10: “Exploring the kinome with kinase broad screening”
Gary Tresadern (Janssen R&D, Beerse, Belgium)
10:00 IS11: “Antibiotic Treatment of Tuberculosis: Old Problems, New Solutions”
Mónica Cacho Izquierdo (GlaxoSmithKline, Madrid, Spain)
10:30 Coffee Break
11:00 Oral Communications (OC9-OC12)
OC9: "Design of mycobacterium tuberculosis shikimate kinase inhibitors inspired by the enzymatic movements for catalytic turnover”
Verónica Prado (CIQUS, Universidad de Santiago de Compostela, Spain)
OC10: “From hit to lead in search of new inhibitors of the enzyme isoprenylcysteine carboxyl methyltransferase (ICMT)”
Silvia Ortega-Gutiérrez (Universidad Complutense, Madrid, Spain)
OC11: “Design, synthesis and biological evaluation of cyclic acylguanidines as bace-1 inhibitors: effect of ring size on activity and selectivity versus BACE-2”
Myriam Ciordia (Janssen Pharmaceutical Research & Development, Toledo, Spain)
OC12: “-Omics tools for studying changes in metabolic pathways of new drugs”
Isidre Masana (Agilent Technologies)
12:00 SEQT Meeting
13:00 Lunch
AFTERNOON SESSION
Chairperson
Concepción González Bello/Antonio Pineda
15:00 IS12: “ETP-CNIO Academic Early Drug Discovery: PIM Kinase Inhibitors”
Joaquín Pastor (CNIO- Centro Nacional de Investigaciones Oncológicas, Madrid, Spain)
15:30 OC13 “Different levels of apoptosis caused by enantiomers in breast cancer cells”
Joaquín M. Campos (Universidad de Granada, Spain)
15:45: Poster Session and Coffee
16:45 Oral Communications (OC14-OC16)
OC14: “Tumor vascular disrupting agents: identification and optimization of novel hits”
Mª Dolores Canela (Instituto de Química Médica, CSIC, Madrid, Spain)
OC15: “3-Substituted indole derivatives as antimitotic agents”
Raquel Álvarez Lozano (Universidad de Salamanca, Salamanca, Spain)
OC16: “Chemical biology for drug discovery: two case studies in drug repurposing”
Jordi Quintana (Parc Científic de Barcelona, Spain)
17:30 Concluding Remarks. Poster and Oral Communication Awards
21:00 Gala Dinner
Gala dinner will be held in "La Posada de la Villa”, a classic Spanish restaurant in Madrid. It is included in the distinguished Michelin Guide) and has been awarded in many occasions: Grand Collar Gourmet, the Chaîne des Rotisseurs, etc.
Posada de la Villa Restaurant C/ Cava Baja, 9. Underground: La Latina metro station.
Important information about posters:
- Poster session 1: Thursday October 3rd 15:45-16:45: ODD numbers
- Poster session 1: Friday October 4th 15:45-16:45: EVEN numbers